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View Full Version : C11H12N2S - Levamisole - Will it decay?


JPMagyar
12/28/2014, 01:29 PM
Randy,

Is there a way to estimate or calculate if and/or how quickly this molecule would decay in the water column of a reef? Might there be some way to test for the presence of this molecule through some type of titration?

My reef is infected with AEFWs and I would like to set up several tanks to test possible solutions. My first thought is to keep a very low level of Levamisole in the water continuously for a period of 2 to 3 weeks, but I have no idea how often I would need to dose to maintain a constant level of levamisole in the water or whether each progressive dose would simply be increasing the overall level. I intend to run neither GAC nor a skimmer for the entire 3 week test.

Anything you can offer, even an educated guess, would be helpful. Thanks.

http://upload.wikimedia.org/wikipedia/commons/thumb/c/c0/Levamisole_ball-and-stick_animation.gif/200px-Levamisole_ball-and-stick_animation.gif

bertoni
12/29/2014, 02:56 PM
Hmm, no takers. I'm sorry, I have no idea how long it'd take for levamisole to break down.

disc1
12/29/2014, 03:01 PM
Me either. But there have been enough people treat tanks with levamisole that a good protocol should be spelled out somewhere around here.

Lavoisier
12/29/2014, 03:21 PM
Please excuse my ignorance, I did a couple of searches but still not clear on what AEFW is exactly.

disc1
12/29/2014, 03:59 PM
Acro Eating Flat Worms

JPMagyar
12/30/2014, 07:51 AM
Please excuse my ignorance, I did a couple of searches but still not clear on what AEFW is exactly.

http://i927.photobucket.com/albums/ad115/JoePeck66/AEFW/IMG_1656_zps30eefaae.jpg


Taxonomy and life history of the Acropora-eating flatworm Amakusaplana acroporae nov. sp. (Polycladida: Prosthiostomidae)
(http://link.springer.com/article/10.1007%2Fs00338-011-0745-3)

There are dozens of threads and articles detailing attempts to find an in tank solution to this problem. Most have centered on varying doses of a drug used for de-worming livestock called Levamisole/Prohibit, but truthfully nothing has been shown to be 100% effective yet. Some folks claim to live with these in their tank, but the only local reefers I know that tried this ultimately gave up and shut down their reefs. I'm close to setting up a new tank and transferring all my acros or frags of my acros to the new tank. It appears that one can "dip" the corals and get a 100% kill rate, but the dips are too caustic for a whole tank treatment.

Randy Holmes-Farley
12/30/2014, 09:15 AM
I have no way to know the breakdown rate in an aquarium. Sorry.