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mnmnm1951-I'd say go for it. Just keep the edge of the holes at least 1 1/2 diameter of hole being drilled from edge of glass and at least 1/2 of diameter of hole distance from nearby hole. This is per a previously posted response on this thread. Each end glass of my 300 was drilled with four 1 7/8 holes, two 2 5/8 holes and one 3 3/16 hole for a total of 14 holes. I wanted both sides for viewing. Each end will support an Ocean Motions 4-way and two 1 1/2 drains from a weir type overflow.
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