Erythromycin is an antibiotic, not an oxidizer. It's more likely to be a bit of a reducing agent, actually. I've never measured oxygen in conjunction with dosing an antibiotic, but I doubt there's be much change unless there was a very large amount of decaying cyanobacteria remnants in the water column.
That said, adding oxidizers can lead to a drop the oxygen level in a tank if the oxidizers kill enough organisms.
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Jonathan Bertoni
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