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IO is a good salt, but once you start keeping corals you may find that you need to suppliment some items fairly heavily. My personal tank maintenance got much easier, and my levels more constant when I went to Reef Crystals. With reef crystals the only thing that seems to get out of range for me is alk. I am just about to try a bucket of Red Sea Reef Pro, so will see how that goes.
In general though, if you heavily suppliment your tank, and monitor levels of Mg, Ca, alk, etc, you can really make any salt work.
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