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If you think you might ever want to use any kind of reactor, as mentioned earlier, go ahead and T off the return line and with a couple ball valves, create a small manifold that you can use to plumb in the reactors.
You might eventually want to use calcium/carbon/gfo reactors (or add a fuge, or add another tank to your system, etc.) and this is the perfect opportunity to prepare for them for very little cost $$. Until you add reactors, the outlet from the manifold can be controlled by the valve on it and directed to flow back into the sump just below the water line so no splashing occurs.
As said already though, valve restriction is just like head pressure, so it shouldn't hurt the pump, to a point.
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