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The carbon is perfectly harmless. The problem is that it does remove copper, and reduces the copper below theraputic levels. Cupramine is the most effective and safest copper treatment available, hands down. Adding any other copper containing substance while treating with Cupramine is incomprehensibly foolish. Small amounts of Prime (not an "overdose") are not dangerous, though adding anything besides the medication itself is unwise. Before medicating you should know what condition you are treating. Shotgun treatment approaches are a bad idea, for fish or humans.
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